by Johanna Schneider - Holistic Health Coach Why Your Gut Plays a Key Role in Your Cycle Many women believe that their estrogen levels depend solely on the ovaries. The truth is: your gut plays a crucial role in how much estrogen is active in your body. A central concept here is the estrobolome — a specific group of gut bacteria that play a key role in regulating estrogen. And this is exactly where the connection to: PMDD (a disrupted estrobolome can amplify hormonal fluct